An exclusive sit-down interview with first lady Melania Trump.

DNA detective CeCe Moore's use of crime scene evidence and a genealogical website leads to an arrest in a cold case from 1992.

An investigation into the synthetic opioid fentanyl, which has been linked to thousands of deaths across the country; the search for undercover labs in China that are responsible for online sales and shipping of the drug.

Interview with Elizabeth Thomas, who was taken at age 15 by her Tennessee high school teacher, resulting in a 38-day nationwide manhunt.

Stories of Americans who followed their dreams and started new careers later in life, including a woman who quit her finance job to pursue acting, and a woman who became the oldest person to graduate from the Houston Police Academy.

A high school cheerleader is shot by an ex-boyfriend who claims it was an accident during an attempt to get her back.

DNA detective CeCe Moore helps two people who were abandoned by their mothers after birth locate their biological families.

A reality-TV executive receives a rare hand transplant after losing limbs due to gangrene related to the uncommon and aggressive autoimmune disease that almost killed him.

Tracking families that have been affected by severe attachment to digital devices, from the height of unmanageability to the journey toward recovery.

"Dateline" has been a staple of the newsmagazine genre since premiering in 1992. Given how long it's been on the air, the show has an extensive archive of in-depth news stories and investigative journalism. This syndicated version offers viewers another chance to watch some of the show's previous content, serving up real-life mysteries and in-depth investigations from the show's 20-plus years on the air. Cases involving murders and missing people are frequent topics on the series that has won multiple Emmys in the news and documentary category.

Anchored by Lester Holt, "Dateline" is NBC's signature newsmagazine, bringing viewers storytelling at its best by putting the pieces together to present the full picture of real-life events. NBC News correspondents cover compelling stories and issues of the day, ranging from mystery and crime to in-depth investigations and breaking-news events.

The oldest and most-watched newsmagazine on television gets the real story on America's most prevalent issues. CBS News correspondents contribute segments to each hourlong episode. Topics range from hard news coverage to politics, lifestyle, pop culture, business, health, and science. The correspondents and contributors include Sharyn Alfonsi, Anderson Cooper, Steve Kroft, Lara Logan, Norah O'Donnell, Scott Pelley, Charlie Rose, Lesley Stahl, Jon Wertheim, Oprah Winfrey and Bill Whitaker.

This newsmagazine investigates intriguing crime and justice cases that touch on all aspects of the human experience. Over its long run, the show has helped exonerate wrongly convicted people, driven the reopening -- and resolution -- of cold cases, and changed numerous lives. CBS News correspondents offer an in-depth look into each story, with the emphasis on solving the mystery at its heart. The program and its team have earned critical acclaim, including 20 Emmys and three Peabody Awards.