Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
After going through a rough breakup, awkward and upbeat Jess (Zooey Deschanel) moves in with three single guys. Intelligent and witty Nick is an underachiever who took the bartender off-ramp on his road to success. Schmidt obsesses over his social standing and looks at Jess as a personal project. Winston is a competitive former athlete who, after realizing he will never become a pro, moves into the loft. Together with Jess' best friend, Cece, they bond to form an unlikely, and dysfunctional, family.
Mike, a Chicago police officer, meets fourth-grade teacher Molly one day when he speaks at an Overeaters Anonymous meeting and they fall in love, thanks in part to their mutual love of pie and the desire to resist it. Both face challenges in their quest to lose weight -- Molly from her slender sister and mother and Mike at the diner where he frequently eats. But having found each other, they will support each other as they try to achieve their goals, be it weight loss or Molly's decision to quit teaching and pursue her dream as a writer.
Ted has fallen in love. It all started when his best friend, Marshall, drops the bombshell that he plans to propose to longtime girlfriend Lily, a kindergarten teacher. Suddenly, Ted realizes that he had better get a move on if he hopes to find true love. Helping him in the quest is Barney, a friend with endless -- often outrageous -- opinions, a penchant for suits and a foolproof way to meet women. When Ted meets Robin, he is sure it's love at first sight, but the affair fizzles into friendship. Voice-over by Bob Saget ("Full House") tells the story through flashbacks.
Single mom Christy has her hands full with two children, Violet and Roscoe, and maintaining newfound sobriety, when her passive-aggressive, recovering-alcoholic mother re-enters the picture, brimming with criticisms about Christy's life. As the daughter works to be the best mother she can and to overcome mistakes she made, she must also navigate dysfunctional relationships with romantic interests, and with her irresponsible ex-husband, Baxter. Despite the uphill battle, Christy tries to remain positive and stay on a path to help her reach her goals.
Surprise! You're a father! Bartender Ben comes home one day and finds that an ex-girlfriend has left a baby girl on his doorstep. The addition to Ben's family -- or having a family -- turns his life upside down. As a New York bachelor in his 20s, being a single dad doesn't fit his lifestyle. After much deliberation, Ben decides to raise the baby with help from his buddy Tucker, brother Danny, and hovering mom Bonnie. Also law student Riley -- once chubby, now slim -- wants Ben to take notice of her, but it's Danny who does.
Detective Jake Peralta, a talented and carefree cop with the best arrest record, has never had to follow the rules too closely or work very hard. That changes when Ray Holt, a man with a lot to prove, becomes the new commanding officer of Brooklyn's 99th precinct. As Holt reminds Peralta to respect the badge, an extremely competitive colleague -- Detective Amy Santiago -- starts to close in on the hotshot cop's arrest record. Other members of the precinct include Sgt. Terry Jeffords, a devoted family man, Detective Charles Boyle, a hard worker who idolizes Jake, and Rosa Diaz, a sexy-yet-intimidating detective. Civilian office manager Gina Linetti is tasked with cleaning up everyone's mess, while somehow getting involved in everyone's business.
Three young men and three young women - of the BFF kind - live in the same apartment complex and face life and love in New York. They're not above sticking their noses into one another's businesses and swapping romantic partners, which always leads to the kind of hilarity average people will never experience - especially during breakups.
An oddball family of employees at supersized megastore Cloud 9 tackles the day-to-day grind of rabid bargain hunters, riot-causing sales and nap-worthy training sessions. Stalwart employee Amy is just trying to hold it all together despite the best efforts of her daftly clueless manager Glen and his iron-fisted assistant Dina. Rounding out the crew is new hire Jonah, a dreamy dreamer, sardonic Garrett, ambitious Mateo and sweet young mother-to-be Cheyenne. From bright-eyed newbies to seen-it-all veterans, bumbling seasonal hires and in-it-for-life managers, they're all going to get through another day -- together.