Several friends own Paddy's Pub, a neighborhood bar in Philadelphia, and try to find their way in the world of work and relationships. But often, they can't get out of their own way, leading to uncomfortable situations, which usually worsen before improving. The gang includes twin siblings Dennis and Sweet Dee Reynolds, along with their longtime friends, Charlie Kelly and Ronald "Mac" McDonald. Charlie lives with Frank, Dennis and Sweet Dee's father, who has left his cheating, money-grabbing wife in an attempt to redeem himself after a history of doing business with sketchy people.
The wealthy town of Westport, Conn., is full of cookie-cutter mommies and their seemingly perfect offspring, but the members of the Otto family can't be counted among them. Confident housewife Katie Otto shares a home with her husband, Jeff, and their three children Taylor, Harrison and Anna-Kat, and while she loves them all dearly, she recognizes they probably aren't going to land themselves in a magazine spread anytime soon. The matriarch knows her family is beautifully flawed, and she's far from sorry.
College facilities manager Dan Chambers is misunderstood, but when he discovers time travel, he finds that he can claim movie quotes and stand-up bits as his own and be the cool guy in the 18th century. He doesn't initially realize that by transporting himself back in time to hang out with his girlfriend, Deborah, he is altering events in the present. When Dan's meddling leads to Paul Revere postponing his famous ride and altering the events of the American Revolution, he must turn to popular history professor Chris Parish for help. Together, Dan, Deborah and Chris try to set everything right.
The close-knit, Chicago-based O'Neals seem to be the perfect Catholic family, but when surprising truths come to light, some lives take an unexpected turn. Eileen, Pat, Kenny, Jimmy, Shannon and Jodi decide to let the honesty ring in a new, less tidy chapter of their story, where they all drop their carefully honed facades and discover the unexpected freedom that accompanies just acting real. Instead of being torn apart, the O'Neals find that their newfound way of life actually brings them closer together.
After going through a rough breakup, awkward and upbeat Jess (Zooey Deschanel) moves in with three single guys. Intelligent and witty Nick is an underachiever who took the bartender off-ramp on his road to success. Schmidt obsesses over his social standing and looks at Jess as a personal project. Winston is a competitive former athlete who, after realizing he will never become a pro, moves into the loft. Together with Jess' best friend, Cece, they bond to form an unlikely, and dysfunctional, family.
Accomplished actors Dianne Wiest and James Brolin star as the heads of a large, happy family, in which each member is approaching different milestones. Their eldest daughter, Heather (Betsy Brandt) and her husband consider having another child as they get closer to an empty nest; middle child Matt (Thomas Sadoski) thinks he has found true love; and the youngest of the three siblings, Greg (Colin Hanks) is overwhelmed after having his first child with his wife. Various perspectives are employed as each family member's story unfolds.
Early '90s band The Heathens lived up to that name offstage as well as on it, partying hard and using drugs. Led by Johnny Rock, the group was on the brink of fame with the release of its first album. Then, the band broke up -- on the day of the album's release -- because lead guitarist Flash discovered Johnny in bed with his wife. "Sex&Drugs&Rock&Roll" picks up the story a quarter-century later when the drugs Johnny is using are of the prescription variety rather than cocaine and marijuana. He's out of work, money and options -- until young singer Gigi, who has a burning desire for fame, shows up with a stack of cash and an offer to get the band out of obscurity and back into the studio. The only catch is that she wants to be the lead singer, and Johnny must stay out of the spotlight as a songwriter.
Bob Belcher is a third-generation restaurateur who runs Bob's Burgers with his loving wife and their three children. Bob believes his burgers speak for themselves and isn't afraid to offer a variety of off-beat creations. Bob's wife, Linda, supports his dream but is becoming sick of the slow times, as the restaurant is constantly in danger of going out of business. Despite the challenges, which includes consistent harassment from Linda's ex -- a health inspector -- Bob tries to keep the grill sizzling.