It's 1989 and 9-year-old Sheldon Cooper has skipped four grades to start high school along with his less-intellectual older brother. As he struggles to be understood by his family, classmates and neighbors, his mother arms him with the best tool she can come up with: reminding bullies his dad is the football coach and his brother is on the team. His twin sister doesn't share his exceptional mind, but she has a much clearer vision of what life has in store for the young genius. Jim Parsons, who plays the adult version of Sheldon on "The Big Bang Theory," narrates.
This long-running animated comedy focuses on the eponymous family in the town of Springfield in an unnamed U.S. state. The head of the Simpson family, Homer, is not a typical family man. A nuclear-plant employee, he does his best to lead his family but often finds that they are leading him. The family includes loving, blue-haired matriarch Marge, troublemaking son Bart, overachieving daughter Lisa and baby Maggie. Other Springfield residents include the family's religious neighbor, Ned Flanders, family physician Dr. Hibbert, Moe the bartender and police chief Clancy Wiggum.
Chiropractor and single father Alan Harper lives in a beachfront house with divorced Internet billionaire Walden Schmidt, who bought the house following the untimely death of Alan's brother, Charlie. As they acclimate to their living arrangement, the tightly wound Alan finds himself taking on a mentor role with Walden, whose lifelong dependence on being taken care of has left him a bit naive. Despite his unsuccessful romantic history, Alan also tries to help Walden overcome his limited experiences with dating. Berta, a sharp-tongued, unapologetic housekeeper, is also featured in the series.
Three young men and three young women - of the BFF kind - live in the same apartment complex and face life and love in New York. They're not above sticking their noses into one another's businesses and swapping romantic partners, which always leads to the kind of hilarity average people will never experience - especially during breakups.
Told from the perspective of an unseen documentary filmmaker, the series offers an honest, often-hilarious perspective of family life. Parents Phil and Claire yearn for an honest, open relationship with their three kids. But a daughter who is trying to grow up too fast, another who is too smart for her own good, and a rambunctious young son make it challenging. Claire's dad, Jay, and his Latina wife, Gloria, are raising two sons together, but people sometimes believe Jay to be Gloria's father. Jay's gay son, Mitchell, and his partner, Cameron, have adopted a little Asian girl, completing one big -- straight, gay, multicultural, traditional -- happy family.
Street-wise Max (Kat Dennings) doesn't expect much from the new waitress at her night job, a rich girl who has reluctantly joined the food service industry after a string of bad luck. But to her surprise, Caroline (Beth Behrs) is a woman of substance and just may be her ticket to success. The two strike up an unlikely friendship after Caroline discovers that Max can bake a mean cupcake, and the women decide if they can just wrangle up the start-up cash, they may have found their big break. Their co-workers at the diner are boss Han Lee, cook Oleg and cashier Earl.
Ted has fallen in love. It all started when his best friend, Marshall, drops the bombshell that he plans to propose to longtime girlfriend Lily, a kindergarten teacher. Suddenly, Ted realizes that he had better get a move on if he hopes to find true love. Helping him in the quest is Barney, a friend with endless -- often outrageous -- opinions, a penchant for suits and a foolproof way to meet women. When Ted meets Robin, he is sure it's love at first sight, but the affair fizzles into friendship. Voice-over by Bob Saget ("Full House") tells the story through flashbacks.
In the Heck family, middle-age, middle-class, middle-America mom Frankie Heck (two-time Emmy winner Patricia Heaton) uses a sense of humor to try to steer her family through life's ups and downs as she tackles her career goals. Her unflappable husband, Mike (Neil Flynn), is a manager at the local quarry. Oldest son Axl is an obstinate young man; awkward daughter Sue cannot seem to find her niche -- despite much enthusiasm in her attempts -- and youngest son Brick is an unusual child whose best friend is his backpack.
After going through a rough breakup, awkward and upbeat Jess (Zooey Deschanel) moves in with three single guys. Intelligent and witty Nick is an underachiever who took the bartender off-ramp on his road to success. Schmidt obsesses over his social standing and looks at Jess as a personal project. Winston is a competitive former athlete who, after realizing he will never become a pro, moves into the loft. Together with Jess' best friend, Cece, they bond to form an unlikely, and dysfunctional, family.
Single mom Christy has her hands full with two children, Violet and Roscoe, and maintaining newfound sobriety, when her passive-aggressive, recovering-alcoholic mother re-enters the picture, brimming with criticisms about Christy's life. As the daughter works to be the best mother she can and to overcome mistakes she made, she must also navigate dysfunctional relationships with romantic interests, and with her irresponsible ex-husband, Baxter. Despite the uphill battle, Christy tries to remain positive and stay on a path to help her reach her goals.