Widowed suburbanite Nancy Botwin (Mary-Louise Parker) starts growing and selling marijuana to make enough money to support her family after her husband's unexpected death leaves her in big debt. Nancy has associates in her pot-growing business, which include Andy, who is her brother-in-law, and pot-smoking City Councilman Doug Wilson. Then there's the business of trying to keep the whole thing secret from people like her neighbor Celia.
Mindy Lahiri is a successful, skilled doctor, but when she leaves the office, all bets are off. She aspires to become a more well-rounded woman, someone who is punctual, frugal and well-read instead of someone who is obsessed with romantic comedies and likely to give an inappropriate toast at a wedding. Despite stumbles, Mindy remains determined to get her personal and romantic life on track -- before her friends and colleagues are forced to stage an intervention -- and find her perfect happy ending.
It's a generational clash when 40-something ad exec Thom Payne gets a new wunderkind boss, who is in his mid-20s. When his boss starts using words like digital, social and viral, Thom realizes he may need to rebrand himself to compete in a technology-driven world. His pursuit of happiness is going well to this point -- he has a beautiful house in the woods, a loving family, a roster of big-name clients and a trophy shelf filled with awards for his work -- but being slow to adapt compromises his quest. His immediate supervisor, 50-something Jonathan, has begun to embrace the changing environment and encourages Thom to do the same. Otherwise, Thom may be stuck being just "happyish" for the rest of his life.
Charming, fast-talking consultant Marty Kaan and his MBA-toting colleagues charm smug, unsuspecting corporate fat cats into closing deals while spending a fortune for their services. Kaan isn't above using any means -- or person -- necessary to get what he wants. Members of his team are razor-sharp Jeannie van der Hooven, an Ivy League alumna; lackadaisical Clyde Oberholt, who's a lady's man; and math guru Doug Guggenheim, who's awkward with women. Marty lives with his psychoanalyst father, son Roscoe and, as of Season 5, his baby daughter.
David Duchovny returns to series television in this adult sitcom as Hank Moody, an alcoholic, womanizing novelist struggling to help raise his precocious daughter, Becca, while still yearning for his sophisticated ex, Karen. Also featured in the show are Hank's agent, Charlie, and his one-time wife, Marcy.
A night-shift doctor at San Antonio Memorial, T.C. Callahan struggles to find the balance between saving lives and the hard reality of running a hospital. Joining him as he faces the sometimes dangerous task of running the emergency room are his best friend -- who often shoulders the unenviable job of keeping T.C. out of trouble -- former Army medic, Drew; lead physician -- and T.C.'s ex-girlfriend -- Jordan; and surgical resident, Paul. The rigors of the job may expose some personal weaknesses, but their shared drive to save their patients bonds them together in a tight-knit group.