In this reimagining of the classic Dracula story, the world is dominated by vampires, requiring humans to work together to survive. The series centers on Vanessa Helsing, daughter of famed vampire hunter Abraham Van Helsing, who wakes up after a five-year coma to discover a vampire-controlled world. She soon learns that she possesses a unique blood composition that makes her immune to vampires and able to turn the creatures into humans. That power puts humanity's last hope to return the world to how it once was before the vampires took over in Vanessa's hands.
In the not-too-distant future, Los Angeles has been invaded and occupied by outside forces, causing a rift between the city's residents; some have collaborated with the occupation, while others are rebelling and suffering the consequences that come with that choice. Former FBI agent Will Bowman and his wife, Katie, must consider their familial obligations when making their decision because they were separated from their son, Bram, during the invasion. Proxy Snyder, a cunning and powerful leader within the occupational government, offers Will the opportunity to get Bram back if he works with the invading faction. Will's decision doesn't sit well with Katie, but the couple risk their lives -- and their relationship -- to protect their family.
The marriage of investment banker Neil Truman and his wife, Grace, has grown stagnant through the years, a fact driven home for Neil when he discovers that his wife is involved with a male escort. After gaining possession of the escort's phone, he learns what his wife thinks of him and what is motivating her to stray while she contemplates whether their marriage is worth saving or if it is time to move on. The drama series looks to answer the question of what to do when having it all is not enough.
When civilization reaches its apocalyptic end, the Copeland family survives the end of the world as they know it, but what will the new world be like? Turns out it's scary, with supernatural creatures, massive storms and a plague among the things that the Copelands must deal with while facing the rapid decline of the new civilization around them. Patriarch Joshua's study of world cultures comes in handy when he has to help his family survive in the new world as wife Karen, a former Air Force pilot, draws upon her combat skills and survival training to protect her loved ones.
While living in the barrio of Jalisco, Mexico, poor Teresa Mendoza falls in love with a member of a successful drug cartel, hoping the love will help her rise above the hopelessness she feels in her life. When it doesn't happen, she is forced to flee the country after her boyfriend is murdered. She seeks refuge in America, where she teams up with an unlikely person from her past to take down the leader of the drug ring that is after her. Teresa ends up starting her own drug empire, becoming one of the world's wealthiest women in the process. With her success, she discovers that money doesn't fix all of her problems, and she can only depend on herself if she wants to stay one step ahead of others and stay alive.
Portland detective Nick Burkhardt, descended from a long line of warriors known as Grimms, defends his city from magical creatures known as Wesen, which are part human and part animal. Fighting alongside his partner, Hank, colleague Sergeant Wu and friends Monroe and Rosalee, Nick faces off against internal and external forces, including his police captain, Sean Renard.
Young, anti-social computer programmer Elliot works as a cybersecurity engineer during the day, but at night he is a vigilante hacker. He is recruited by the mysterious leader of an underground group of hackers to join their organization. Elliot's task? Help bring down corporate America, including the company he is paid to protect, which presents him with a moral dilemma. Although he works for a corporation, his personal beliefs make it hard to resist the urge to take down the heads of multinational companies that he believes are running -- and ruining -- the world.
A man from the post-apocalyptic future, Cole uses a dangerous, untested method of time travel to get from 2043 to the present day. He is on a mission to locate and rid the world of the source of the plague that will eventually annihilate the human race. Assisting him is Dr. Cassandra Railly, a virologist who must decide whether to do harm in order to save the world -- regardless of the fact that she has taken the Hippocratic oath. The sci-fi series is based on Terry Gilliam's 1995 film, which starred Bruce Willis as Cole.
Dr. Ephraim Goodweather, the head of the CDC's New York-based Canary Project, is called upon to investigate when an airplane lands with everybody on board dead. What his team discovers is a viral outbreak that has similarities to an ancient strain of vampirism. As the virus begins to spread, Goodweather works with his team and a group of the city's residents to wage a war that could hold humanity's fate in its hand. The show's executive producers include Oscar-nominated writer Guillermo del Toro and Emmy-winning producer Carlton Cuse.