Things do not go as planned at Alex and Jo's wedding; the stress from the past year has taken a toll on Bailey, making her re-evaluate some of her decisions.

The doctors rally around one of their own who is seriously injured; Nicole Herman pays a visit and talks to Arizona about an exciting opportunity.

Alex and Jo go on a road trip to Iowa to find Alex's mom; Meredith gives a presentation on her mini-livers project, which attracts a lot of attention.

The hospital brings in crisis management to help sort out allegations against Harper Avery; nurse Olivia shows up at Grey Sloan with her son, throwing Alex and Jo for a loop; Sofia is having a hard time at school.

Arizona shares some cookies that, unbeknownst to her, contain a special ingredient; Catherine reveals some shocking details to Jackson; Jo comes into the surgical room at mid-operation of a major surgery.

Practically raised at Seattle's Station 19, Andy Herrera is a confident firefighter who is also the daughter of Pruitt Herrera, the formidable head of the firehouse. Capt. Pruitt was Andy's primary inspiration to become a firefighter and is a mentor to both her and Jack Gibson, the lieutenant at the station. Jack is as fearless as Andy is by-the-books, but when the two are together, sparks fly and opposites attract. The two are joined by Maya Bishop, Dean Miller, Travis Montgomery, Victoria Hughes, and the station's newest addition, rookie Ben Warren. The team also works closely with Seattle PD, often running into Andy's former flame Ryan Tanner.

At fictional Princeton Plainsboro Teaching Hospital in New Jersey, prickly genius Dr. Gregory House tackles health mysteries as would a medical Sherlock Holmes, all the while playing mind games with colleagues that include his best friend, oncologist James Wilson. House, an acerbic infectious disease specialist, solves medical puzzles with the help of a team of young diagnosticians. Flawless instincts and unconventional thinking help earn House great respect, despite his brutal honesty and antisocial tendencies.

"Grey's Anatomy" creator Shonda Rhimes is the creative mind behind this ABC drama. Olivia Pope, a former media consultant to the president, is ready to move on with her life and opens her own crisis-management firm, but she can't seem to shake ties with her past. Olivia's staff includes Quinn Perkins, who has a complicated history, and hacker extraordinaire Huck. As she moves forward it becomes clear that, while her staffers may specialize in cleaning up the lives of other people, they can't seem to do the same for themselves.

Annalise Keating (Oscar- and Tony-winning actress Viola Davis), a brilliant, charismatic and seductive professor of defense law, teaches a class called How to Get Away With Murder. Annalise, also a criminal defense attorney, selects a group of students -- the best and the brightest -- to assist with cases at her firm alongside her employees, the trustworthy and discreet Frank Delfino (Charlie Weber) and Bonnie Winterbottom ("Gilmore Girls" alum Liza Weil), an associate attorney. Mysteries arise that test everyone's limits and reveal dark truths.

Set in Chicago, this medical drama deals with the personal and professional crises of the doctors in the emergency room at County General Hospital. From the exciting to the mundane, a day in the frantic hospital serves up many interesting dilemmas as well as heartrending choices for everyone on staff.

Conrad Hawkins is one of Chastain Park Memorial Hospital's best doctors. Charming and arrogant, Conrad likes to take an unconventional approach whenever possible and believes it's his personal duty to shatter the romantic illusions of the first-year residents. Dr. Devon Pravesh is an innocent idealist who leans on his finely tuned moral compass, but with Conrad's help, he begins to realize that the practice of medicine is a business, like any other, with less-than-angelic patients and fallible doctors.

Based on the award-winning documentary of the same name, this medical drama follows the staff members in the nation's busiest emergency room as they cope with a staggering influx of patients, which can outweigh their limited resources, resulting in a condition known as code black. Residency Director Dr. Leanne Rorish -- who is known for her success with high-risk procedures in the trauma area -- leads residents Malaya and Angus, among others. Senior nurse Jesse Sallander manages the residents and serves as Leanne's confidant, with doctors Rollie Guthrie, Will Campbell and Heather Pinkney rounding out the group. Together, the doctors and nurses race to save lives in an overwhelmed system.