When sisters Beth and Annie and their best friend Ruby become fed up with playing by the rules and not getting the respect they deserve, they band together to take control of their lives -- by holding up a local grocery store. Beth's the perfect wife and mother, but her used-car-dealing, cheating husband has sent her family into financial ruin; Ruby is happily married to a policeman but can't afford the medical bills and experimental drugs to help her daughter; and Annie, a single mom, is caught in a nasty custody battle with her ex. In desperate need of money, the women plan the heist expecting to ease their financial burdens. But new to the game of crime, they get pulled in deeper than they ever imagined -- and the only way out of this will be together.
Fearing for their lives, the ladies scramble to try to take down Rio; a kidney becomes available for Sara but Ruby and Stan don't have the money to pay for it; a plan is hatched to solve both problems.
Rio asks the women to do a job so he can get the operation up and running, but they fear there may be more to the task than meets the eye; Ruby learns that Sara has risen to the top of the transplant list.
Beth, Ruby and Annie attempt to go back to being ordinary housewives after Rio abruptly shuts down operations; Mary Pat puts a financial squeeze on them -- forcing the three women to commit another heist.
The women get a reminder of how violent Rio can be; Beth and Ruby both enjoy the shifting dynamics in their respective marriages; Boomer carries out a malicious plot against Annie that puts her fight for custody in jeopardy.
Overwhelmed by the sheer volume of work their new enterprise demands, the ladies decide to outsource; while their business flourishes, the women's personal lives spiral; Dean confronts Beth; Stan discovers Ruby's been lying to him.
Beth struggles to keep her new business separate from her home life; Annie's loneliness leads her to an ill-advised one-night stand; Ruby doubles down on her lies to Stan; FBI Agent Jim Turner follows up on Boomer's tip about the women.
Beth comes home to a surprise guest; Beth throws Kenny an elaborate birthday party; Ruby's employment at the diner is threatened by a disgruntled teenage customer; Annie comes up with a creative solution for dealing with bullies.
Beth, Annie and Ruby bite off more than they can chew when they agree to help Rio smuggle contraband; Ruby deals with a so-called family friend; Annie prepares for a visit with a social worker that could affect her custody battle with Greg.
The women struggle to come up with the money they owe the gang; Annie's fight for custody takes a major hit; Beth tries to navigate life as a single parent; Ruby's concerns for Sara's health escalate.
Three desperate suburban moms find themselves in hot water after they decide to rob a supermarket and find out that it's already the territory of a local gang.