After a massacre of several monks at a Buddhist temple in Arizona, the police are shocked to discover the man arrested for the crime is not the actual killer.

Police uncover a string of murdered prostitutes, each of which have had their eyes carved out.

What was supposed to be a routine motorcade for the Queen of England, turns into a car collision killing three Secret Service Agents.

A young mother is sexually assaulted and killed in her home, the killer was meticulous in washing everything, but left behind a single hair.

A high school student disappears, then a prostitute is murdered causing police to believe they may be linked.

A real estate developer is shot and his wife becomes the prime suspect, until the bullet is linked to a weapon reported missing 20 years ago.

A man is found dead of an apparent slow suicide but information emerges which reveals that his wife may have had a more prominent role in his death, especially since her first husband died so young and she refused to consent to an autopsy.

A husband saves his wife and child from a burning trailer, but one month later she is killed in her sleep, all evidence leads to the husband.

A young bride-to-be is gunned down in her own home; the attack is personal and as investigators start digging, they uncover the man she loved was living a lie.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A mask is discovered near the crime scene and police are hoping that it will lead to the killer of a funeral director.

When a young woman disappears, police think an abusive ex-boyfriend is to blame.

The killer removed the computer that links him to the murder of a woman and her soon-to-be ex-husband that he had met online.

Four young adults are murdered and the crime scene yields little results, until a neighbor reports seeing two people in black the night of the crime.

An Ohio woman and her two daughters go missing while vacationing in Florida; their corpeses are found floating in Tampa Bay with a hand-written note by one of the victims by. putting it on five billboards to helps them find the killer.

Community searches deliver devastating results when a teenage girl goes missing, investigators begin hunting a killer.

A man perishes in a fire while working in his garage and his death is initially ruled an accident until a Forensic Odontologist changes the direction of the case.

Evidence that includes threatening emails, a missing person and an abandoned truck lead police to what they believe is a killer, but they don't have the body of the victim.

A 12-year-old is the only witness to her mother's death and is unable to provide investigators with many details in Maine.

After a prominent Arizona surgeon is found stabbed to death outside his office, investigators uncover an unlikely suspect with deep pockets and an even deeper hatred for the doctor.

After a young scientist dies from a mystery illness, investigators discover evidence in his hair that might help identify his killer.

Victims' rights activist John Walsh returns to weekly TV as host of a documentary-style investigation series. Walsh details stories of ongoing cases involving fugitives, with the intent of expanding searches outside the United States. Interviews with victims, loved ones and law enforcement accompany new leads in each hourlong episode, giving the public information to facilitate the capture of suspects. Walsh, a spokesman for the National Center for Missing & Exploited Children, hosted the series "America's Most Wanted" for 25 years, helping apprehend more than 1,200 criminals.

This newsmagazine investigates intriguing crime and justice cases that touch on all aspects of the human experience. Over its long run, the show has helped exonerate wrongly convicted people, driven the reopening -- and resolution -- of cold cases, and changed numerous lives. CBS News correspondents offer an in-depth look into each story, with the emphasis on solving the mystery at its heart. The program and its team have earned critical acclaim, including 20 Emmys and three Peabody Awards.