As a 14-year-old boy in 1991, Alex Riley and his mom move from Chicago to Los Angeles when she remarries. In present day, 40-year-old Alex's life has hit both a personal and professional standstill. In 2042, at 65, Alex has a realization that to be truly happy, he has to step away from his successful company and get back to his passion... inventing. "Me, Myself & I" follows him through each of these pivotal periods, revealing where the past informs the future, and the moments where he learns that his story isn't defined by what happens to him, but by how he decides to deal with it.
Childhood best friends Maggie Caruso and Emma Crawford have shared countless adventures raising Maggie's daughter Charlotte together in their hometown of Pinebrook. The BFFs overcome unexpected hurdles since Emma's move back home to help Maggie, including navigating colorful characters from their past and surviving countless dating misadventures. Now, the tables are turned when Maggie needs to come to Emma's rescue as their friendship faces its biggest challenge yet. These women complement each other the way only best friends can, by facing the challenges of their past, present and future -- together.
The wealthy town of Westport, Conn., is full of cookie-cutter mommies and their seemingly perfect offspring, but the members of the Otto family can't be counted among them. Confident housewife Katie Otto shares a home with her husband, Jeff, and their three children Taylor, Harrison and Anna-Kat, and while she loves them all dearly, she recognizes they probably aren't going to land themselves in a magazine spread anytime soon. The matriarch knows her family is beautifully flawed, and she's far from sorry.
Falling in love with a co-worker and pursuing a relationship is often a slippery slope that has a high probability of not ending well. So, of course, the best time to announce your love to a colleague is when you're about to begin a job overseas and know you'll never see that person again. That's the route Kevin takes, writing a letter to co-worker Audrey to declare his unrequited love for her after he accepts a position abroad. That opportunity falls through, though, and he is forced to go back to his old job. Can you say awkward? Kevin and Audrey must now continue their working relationship with his previously hidden feelings for her now out in the open.
Emily Locke lands her dream job as director of research and development for Wayne Security in Charm City, home to superheroes, super villains and everyday citizens fed up with the collateral damage of their constant super fighting. Full of confidence and big ideas about how to make life safer for the populace, Emily quickly learns that her aspirations far exceed those of her new boss and officemates, so it is up to her to lead the team toward its full potential and the realization that you don't need superpowers to be a hero.
New Yorker Jill Weber is fighting a battle within herself -- embrace her quirky and unconventional life with husband Andy and their three kids or give in to the temptations and perks afforded to her by Andy's wealthy, blue-blooded family. Increasing the pressure on Jill to conform are status-obsessed mother-in-law Candace and brother-in-law Lex, along with his wife, Brooke, who reigns over a group of Upper East Side mothers who aren't afraid to whip out their credit cards to buy whatever they want. Jill tries to stay true to herself while giving in to temptations, using the Weber family legacy to do things like interview for a family plot at a prestigious cemetery. As she deals with her hormonal tweenage daughter, Jill struggles with her desires to feel young and relevant. The series stars author Jill Kargman as Weber, a satirical version of herself.
Up until recently, fiercely independent Alice spent her life with a laser focus on advancing her career. All of that goes out the window when she meets Ben and he -- along with his three children -- gets her to reconsider her long-held priorities. Her life in upheaval, things get even more disconcerting when Mary, the mentally unbalanced imaginary friend she played with as a child, returns and tries to help her with the transition from a single girl to a family woman. Rachel Dratch provides the voice for Mary.