As a lower-level cabinet member, Tom Kirkman never imagined something would happen that would catapult him to the oval office. When a devastating attack on the night of the State of the Union address claims the lives of the president and most of the Cabinet, the Housing and Urban Development secretary -- who was named the designated survivor in case of such an event -- finds himself promoted to leader of the free world. Suddenly thrust into his new position of power, Kirkman struggles to keep the country from dissolving into chaos and must adjust to his new normal, unaware of what fresh horrors may await the United States.
Having left her job as a CIA analyst for ethical reasons, newly appointed Secretary of State Elizabeth McCord returns to public life at the request of the president, after the suspicious death of her predecessor. Valued by her boss for her apolitical leanings, knowledge of the Middle East, language skills and creative thinking, Elizabeth drives international diplomacy, battles office politics and circumvents protocol while negotiating national and international issues. At home, politics and compromise take on new meaning with her supportive husband and three bright kids.
When it is discovered that an enormous asteroid is just six months away from colliding with Earth, MIT grad student Liam Cole and tech billionaire Darius Tanz team up to save humanity from this impending apocalypse -- without ever alerting the public. As part of the project, Darius recruits an aspiring sci-fi writer, Jillian, to work on a theoretical approach to saving humanity. While they try to save the world their way, the government has its own approach, with Deputy Secretary of Defense Harris Edwards spearheading the top-secret plan to deflect the asteroid.
Sam Fox is an actress, who is also a single mother raising three daughters -- teenager Max, eccentric middle child Frankie, and spicy youngest daughter Duke -- in Los Angeles. She also helps to care for her mother, Phil, who lives across the street. In addition to looking after her family, Sam tries to earn a living in the difficult acting industry while having time to have fun with friends and, occasionally, take time for herself to squeeze in some private time. In addition to starring as Sam, Emmy winner Pamela Adlon is a co-creator of the comedy series, along with Louis C.K.
When Kevin retires from the police force, he thinks life will be all about hanging out with his wife and kids and going on the occasional adventure with fellow retirees. A different narrative starts to take shape when he discovers his wife has been protecting him from certain family info while he was out keeping the streets safe. When his wife dies suddenly, Kevin must postpone a life of leisure and work on keeping his family in shape. In addition to taking on the role of single dad, Kevin goes back to work, joining the private security firm launched by his former partner.
Fourteen years after a string of murders committed by an assailant dubbed the Silver Bells Killer terrorized the city of Boston, authorities reopen the case. As the investigation progresses, the Hawthorne family discover that one of their own could be linked to the grisly crimes. As disturbing secrets from the past and present find their way into the light, an atmosphere of mounting suspicion and paranoia that one of them is a killer threatens to tear the family apart.
Young Silicon Valley billionaire James Bell is not one to sit idle and wait for things to happen, so building state-of-the-art Bunker Hill Hospital is the natural progression for his interest in treating rare medical conditions. His Chief of Staff Dr. Walter Wallace, a surgeon with a controversial past, leads a team of trailblazers that includes physician Zoe Brock, neurosurgeon Talaikha Channarayapatra, neurologist Scott Strauss, Malik Verlaine -- a former gang member who now dedicates his time to monitoring health in poor neighborhoods -- and 3-D printer programming expert Angie Cheng.
Adam has been operating under the assumption that his three children are little angels, but when his wife decides to rejoin the workforce after being a stay-at-home mom for 13 years, and he starts taking on more of the parenting responsibilities, he's quickly disavowed of that notion. Kate, a preteen, is a master manipulator and excited to take advantage of her father's naivete; Teddy spends too much time with his hands down his pants; and Emme frets over school. After recovering from the initial shock -- and with the advice of equally stressed parents Marie and Lowell -- Adam is confident he can lay down the law and keep the house in order.